Introduction of O2 to Earth's early biosphere stimulated remarkable evolutionary adaptations, and a wide range of electron acceptors allowed diverse, energy-yielding metabolic pathways. Enzymatic reduction of O2 yielded a several-fold increase in energy production, enabling evolution of multi-cellular animal life. However, utilization of O2 also presented major challenges as O2 and many of its derived reactive oxygen species are highly toxic, possibly impeding multicellular evolution after the Great Oxidation Event. Remarkably, ROS, and especially hydrogen peroxide, seem to play a major (...) part in early diversification and further development of cellular respiration and other oxygenic pathways, thus becoming an intricate part of evolution of complex life. Hence, although harnessing of chemical and thermo-dynamic properties of O2 for aerobic metabolism is generally considered to be an evolutionary milestone, the ability to use ROS for cell signaling and regulation may have been the first true breakthrough in development of complex life. The importance of Earth's oxygen cycle and reactive oxygen species produced on the evolution of complex life. The ability to detoxify oxygen species is not a trait that emerged as a response to increased O2 levels but rather crucial adaptation to the early Earth's weakly oxic microenvironments. (shrink)

Descriptions of body imagery and body parts are evident in expressions of Old Testament texts. Although there is no single term for ‘body’ in the Hebrew mind, the concept of ‘body’ functions in its different parts. As part of anthropomorphic descriptions of God and expressions attached to humankind, body parts have special significance, contributing to the theological dimension of texts. The poems in the Psalter are no exception. Several body parts are mentioned in Psalm 38, an individual lament song. In (...) addition to God’s hand (v. 3) and an allusion to his voice (v. 16), several body parts describe the psalmist’s condition. These include ‘flesh’ (bāšār, 3, 8), bones (‘ætsæm, 3), head (rôsh, 5), loins (kæsæl, 8), heart (lēb, 9, 11), eyes (‘yn, 11), mouth (pæh, 14, 15), and feet (rægæl, 17). In addition, allusions to the ear (14, 15) and injured body (wounds, 6) form part of the psalmist’s lamenting experience.Contribution: This presentation touches on the general meaning of these body imagery in the Old Testament and their specific function and meaning in the text of Psalm 38. A textual analysis will portray their theological significance. (shrink)

“Neo-inclusivism” is explained and assessed as an approach to the problem of the conflicting claims to truth of different religions, with reference to inter alia John B. Cobb (Jr.), Gavin D'Costa and Paul Ingram. For the neo-inclusivist the truth of a religious tradition depends on its inclusivistic capacity, i.e. its capacity to assimilate other traditions. For ex ample, by being enriched and transformed through “radical openness” to other traditions, while remaining “committed” to her own tradition – so the neo-inclusivist claims (...) – the theology of the Christian can become “truly global”. Neo-inclusivism seemingly transcends the absolutist habits of inclusivists, i.e. to assess the religious other in view of criteria (the inclusivist's own religious tradition) with which the other does not identify himself or herself. However, the neo-inclusivist plays down the possible limits of inter religious openness and is overly optimistic about the possibility of a “truly global” theology. Moreover, whether the neo-inclusivist's “committed openness” significantly differs from the approach of those who arbitrarily use the definitive norms of their own religious tradition to assess other traditions, is at least debatable. Whatever the case may be, insofar as tolerance cannot tolerate intolerance, the neo-inclusivist is necessarily intolerant, and, in this sense, “absolutist”, towards those who make their own beliefs normative for all and shun themselves from the assessments and new insights of others. S. Afr. J. Philos. Vol.23(1) 2004: 82-107. (shrink)

How may or should adherents of a particular religion assess other religious traditions? Whether they can avoid both absolutism and relativism depends on the availability of “ecumenical criteria”, i.e. a common scale in view of which the adherents of different religious traditions may jointly judge these traditions. It is argued that such a scale may exist even if we assume that the adherents of the different religions do not have any religious beliefs or criteria in common. This scale may exist (...) insofar as believers may share certain meta-religious criteria, e.g. the coherence of beliefs, their existential relevance and efficiency – i.e. their capacity to meet needs and concerns, including ethical-political and scientific concerns – and the impressiveness of beliefs. As such these criteria coincide with conditions that regulate the effective functioning of religions as ultimate frames of reference. However, it is not assumed that these criteria constitute ahistorical foundations. Adherents of the different religious traditions may not agree on the coherence, the existential relevance and efficiency, or the impressiveness of beliefs. Neither will they necessarily agree that these considerations are appropriate. Whether such an agreement exists will only, if at all, become apparent through inter religious dialogue. S. Afr. J. Philos. Vol.23(3) 2004: 302-326. (shrink)

Do adherents of different religious traditions communicate and, if so, how? What enables them to do so? What is interreligious “communication”? These issues are ad dressed with reference to Wilfred Cantwell Smith's hermeneutical rule, and to inter alia Paul Knitter, Martin Heidegger, Hans-Georg Gadamer, David Tracy, and John Dunne. Four responses to the question as to what permits interreligious communication are criticised. According to a fifth response, on which the author elaborates, interreligious communication is not – as the objectivist claims (...) – possible because members of different religious traditions speak the very same language, or – as the relativist claims – impossible because they speak radically different languages. Adherents of different religions communicate, if at all, by means of an analogical language. This language is the product of persistent efforts to understand the religion/faith of the other as he or she understands it. Paradoxically, the language that permits inter religious communication is thus the product of such communication. Without thereby reverting to objectivism or an essentialist view of religion, the author identifies five “less unstable” similarities between religions. These and other “less un stable” similarities might assist believers in their efforts to under stand the religious other. (shrink)

Offering an overview of challenges and questions, the essay situates contemporary directions and developments in Reformed thought about political ethics by considering whether four well-known slogans from the tradition of Reformed political thought are still meaningful and credible under changed conditions today. The four slogans, integrally related to one another, are the lordship of Christ, the prophetic role of the church, the love for justice, and the importance of calling. The essay draws primarily on recent South African experiences, where the (...) Reformed tradition was deeply involved in both apartheid theology and the church struggle against apartheid. It engages with the North American Reformed philosopher Nicholas Wolterstorff as main interlocutor, since his own interest in political theology and his own convictions about justice and rights also developed in direct engagement with his own South African experiences. (shrink)

We performed an EEG graph analysis on data from 31 typical readers and 24 dyslexics, recorded while they were engaged in an audiovisual task and during resting-state. The task simulates reading acquisition as participants learned new letter-sound mappings via feedback. EEG data was filtered for the delta, theta, alpha, and beta bands. We computed the Phase Lag Index to provide an estimate of the functional connectivity between all pairs of electrodes per band. Then, networks were constructed using a Minimum Spanning (...) Tree, a unique sub-graph connecting all nodes without loops, aimed at minimizing bias in between groups and conditions comparisons. Both groups showed a comparable accuracy increase during task blocks, indicating that they correctly learned the new associations. The EEG results revealed lower task-specific theta connectivity, and lower theta degree correlation over both rest and task recordings, indicating less network integration in dyslexics compared to typical readers. This pattern suggests a role of theta oscillations in dyslexia and may reflect differences in task engagement between the groups, although robust correlations between MST metrics and performance indices were lacking. (shrink)

The idea of the spherical world, poised in space, and encircled at different distances by the celestial bodies, was introduced by the early Greek cosmologists. With some modifications, it is still our Western world-picture. It differs fundamentally from that of other cultures, which all accept, in one version or another, the idea of a flat earth with the dome of the celestial vault above it. The Greek conception, however, entails the problem of falling. How to account for the earth's stability? (...) Why is it that the earth does not fall? This anxious question has already bothered the Presocratics. Aristotle provided the solution that was satisfying for many hundred of years. Falling, according to Aristotle, is not the problem, but the answer, as the earth, consisting of the heaviest of the elements, finds its natural place in the centre of the spherical universe. For the same reason the earth itself, according to Aristotle, has to be spherical. Thus, his main line of argumentation was what we now would call 'metaphysical'. Recently, some scholars have argued that the early Greek idea of a spherical earth was developed as a protoscientifie hypothesis, based on empirical reasoning and observation. In this article, we show this to be an example of the 'anachronistic fallacy' that seriously obscures our understanding of the ancient Greek philosophers. Aristotle's conception held for two millennia, until the work of Copernicus, Kepler, and Thomas Digges overthrew it. Consequently, Newton had to cope with the fear of falling again — a fear that still haunts our modern world-picture and that was brilliantly articulated by Blaise Pascal, in his Pensées. (shrink)

The self seems to be a unitary entity remaining stable across time. Nevertheless, current theorizing conceptualizes the self as a number of interacting sub-systems involving perception, intention and action (self-model). One important function of such a self-model is to distinguish between events occurring as a result of one's own actions and events occurring as the result of somebody else's actions. We conducted an fMRI experiment that compared brain activation after an abrupt mismatch between one's own movement and its visual consequences (...) with an abrupt mismatch between one's own movement and somebody else's visually perceived hand movement. A right fronto-parietal network was selectively active during a sudden mismatch between one's own observed and performed hand action. (shrink)

Leaders, particularly new leaders, seek to establish high levels of trust, as it has been associated with higher levels of effectiveness and group outcomes. This study is designed to understand how trust changes and develops for leaders in a new role and the implications of that change. Although calls for research on trust over time have been made for the past 2 decades, our knowledge of this phenomenon is still quite limited. The findings indicate that leader and unit performance is (...) a function not only of absolute trust level, but is also affected by the direction and magnitude of change in trust across time periods, with the highest levels of effectiveness being associated with leaders who exhibited an increase in trust from the group over time. The data also suggest that the direction and rate at which trust grew was determined by initial expectations and transformational leadership behaviors. (shrink)

A much-cited definition of placebo is from Shapiro and Shapiro :"any therapy that is intentionally or knowingly used for its nonspecific, psychological, or psychophysiological, therapeutic effect, or that is used for a presumed specific therapeutic effect on a patient, symptom, or illness but is without specific activity for the condition being treated". What nonspecific means and how it relates to the psyche has been written about extensively yet inconclusively. In the end, the term nonspecific doesn't say anything about the crux (...) of the matter.Talking about placebo, one first has to distinguish between " placebo effect proper" and "perceived placebo effect." The. (shrink)

Recent empirical work indicates that reduced autobiographical memory specificity can act as an avoidant processing style. By truncating the memory search before specific elements of traumatic memories are accessed, one can ward off the affective impact of negative reminiscences. This avoidant processing style can be viewed as an instance of what Erdelyi describes as the “subtractive” class of repressive processes.

ABSTRACTThe question of how to engage with stakeholders in situations of value conflict to create value that includes a plurality of conflicting stakeholder value perspectives represents one of the crucial current challenges of stakeholder engagement as well as of value creation stakeholder theory. To address this challenge, we conceptualize a discursive sharing process between affected stakeholders that is oriented toward discursive justification involving multiple procedural steps. This sharing process provides procedural guidance for firms and stakeholders to create pluralistic stakeholder value (...) through the discursive accommodation of diverging stakeholder value perspectives. The outcomes of such a discursive value-sharing process range from stakeholder value dissensus to low and increasing levels of stakeholder value congruence to stakeholder value consensus. Hence, this article contributes to the emerging literature on integrative stakeholder engagement by conceptualizing a procedural framework that is neither overly oriented towards dissensus nor consensus. (shrink)